Professor Mindiola began his college education at Michigan State University, East Lansing, MI, in 1992. As a "Spartan", he spent the next three and a half years learning the crafts of inorganic chemistry under the auspices of Professor Kim R. Dunbar. After obtaining his B.S. degree in chemistry from MSU in 1996, Professor Mindiola then attended the Massachusetts Institute of Technology in Cambridge, MA, under the guidance of Professor Christopher "Kit" Cummins. In the summer of 2000, Daniel completed his Ph. D. degree and continued work in small molecule chemistry as an NIH and FORD post-doctoral fellow in the laboratories of Professor Gregory L. Hillhouse at the University of Chicago. In 2002, he accepted an invitation to join the Chemistry Faculty at Indiana University in the city of Bloomington, IN. He was promoted to Associate Professor with tenure in 2007, and promoted to Full Professor in 2011.
Mindiola's research work entails the design and assembly of reactive metal complexes of early metals and their role in unusual transformations such as C-H activation and C-N bond cleavage reactions. He is also interested in novel catalytic processes mediated by reactive complexes containing metal-ligand multiple bonds.